Because Good Medicine Deserves Better Explanations
Author’s Note: This article was initially published in 2014. Since then, a growing body of research has strengthened the case for using the triglyceride-to-HDL cholesterol (TG/HDL-C) ratio as a simple, powerful marker of cardiometabolic risk. This 2025 update brings new clinical insight, clearer explanations, and a narrative approach to help readers understand why this ratio … Read more
Triglycerides are important organic compounds. Most of the fat we consume in our diet is triglyceride and so is most of the fat we store in our body. Fatty acids contained in triglycerides are an essential source of energy for human cells. Triglyceride concentration can be measured in blood and may provide valuable information about … Read more
There are several reasons why we should be interested in the amount of cholesterol circulating in our bloodstream. However, to interpret our cholesterol numbers, we have to know certain things about cholesterol and its role in health and disease. What Is Cholesterol? Cholesterol is classified as a sterol (a combination of steroid and alcohol) and … Read more
The recently published results of the long awaited CANTOS trial may forever change our approach to the prevention and treatment of coronary artery disease (1). Inescapably, there is now proof that targeting inflammation, in this case by a drug, significantly improves outcome for certain very high-risk patients. But, as so often in clinical research, things … Read more
I recently gave a talk at a meeting with colleagues, most of them cardiologists and endocrinologists, where I, among other things, discussed the current status of diet-heart hypothesis and the possible relationship between our fear of dietary fats and the obesity epidemic. After the meeting, a senior colleague of mine, an old friend, and a … Read more